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Molecular Biology Platform
Supervisor: Arnauld Efon E.
The molecular biology platform activities are based on molecular diagnostic, molecular entomology, as well as population genetics and bioinformatics. The activities of this platform primarily focus on research of molecular markers for the acute detection of various pathogens, including parasites and viruses. It aims at the diagnosis of infectious diseases and involves all known diagnostic steps including the extraction and purification of nucleic materials (DNA, RNA) using a range of methods and both traditional and real-time PCR.
Molecular entomologies activities are also among the main activities of the platform, consisting in molecular characterization of various arthropods of medical importance (blackflies, mosquitoes, tsetse flies …) and parasites including the assessment of genetic diversity and pathogen genotyping.
Bioinformatics and computational biology are developed as supportive activities of core molecular biology platform activities, and it includes both basic bioinformatics (primers design and evaluation), analysis of sequencing data (genomics and transcriptomics) and predictive biology.
The molecular Biology Platform is equipped with high tech machines for the, including:
- A Real time PCR (Polymerase Chain Reaction) instrument
- A Thermocycler Biorad
- A Nucleic material extraction instrument a Precellys instrument
- A PSM
- A Laminar flow hood
- Trans illuminator equipped with a photo system
- A Fridge for reagent storage