Welcome to the official website of the Higher Institute for Scientific and Medical Research (ISM)

ISM is a non-profit Cameroonian association working in the field of health, better known as CRFilMT (Center for Research on Filariasis and Other Tropical Diseases) and has been created in 2005 by the will of  Professor Joseph Kamgno


In the context of onchocerciasis control, Serious Side Effects (SSEs) have been observed after treatment with ivermectin (Mectizan®) in areas where loasis is co-endemic. This is how ISM was born in 2005, whose best known name is CRFilMT.

Our ambition is to contribute to the resolution of health problems through applied scientific research as well as to develop a system of monitoring, prevention and management of serious side effects occurring after mass treatment campaigns with ivermectin (Mectizan®) for onchocerciasis among others. 


The Departments We Work In

The work of ISM is divided into six distinct departments which are:


Parasitology is the scientific discipline concerned with the study of the biology of parasites and parasitic diseases including the host response to these agents

Molecular biology and

It is the study of the composition and structure
of cellular molecules that carry out the biological processes essential for the cellular functions

Medical entomology

Entomology encompasses the biological, agricultural, and environmental sciences related to insects and their interactions with humans and other organisms


Immunology is the study of the immune system and is a very important branch of the medical and biological sciences

and Biostatistic

It is the branch of medicine which deals with the incidence, distribution, and possible control of diseases and other factors relating to health

Medical center

Medical center is a large health-care facility that provides medical and surgical. We are open every working day

Check out exclusively articles by our researchers

ISM accompanies a team of brilliant researchers whose work has already been praised and appreciated by other organisations on an international scale

Arnauld Efon-Ekangouo, Hugues C. Nana-Djeunga, Philippe Nwane, Elvis Lisongue-Tonga, André Domche, Laurentine Sumo, Mike Yaw Osei-Atweneboana, Anne Geiger, Joseph Kamgno

Alvine Christelle Kengne Fokam, Laurentine Sumo, Mohamed Bagayan, Hugues Clotaire Nana-Djeunga , Thomas Kuete, Gabriella S. Ondoua Nganjou, Murielle Carole Tchami Mbagnia, Linda Djune-Yemeli, Charles Sinclair Wondji and Flobert Njiokou Published Online: October 2022; DOI: 10.5897/AJB2022.17505

Lionel Ulrich Tiani, Axel Cyriaque Ambassa, Jean Paul Assam Assam, Genevieve Andoseh, Francis Zeukeng, Cedric Tchinda Fossi, Tsasse Martine Augusta Flore, Leonard Nkah Numfor, Hortense Gonsu Kamga, Charles Kouanfack, Eric Walter Pefura Yone, Marceline Djuidje Ngounoue, Jude Daiga Bigoga, Francine Ntoumi and Véronique Penlap Beng. Published Online: September 2022; DOI: 10.5897/AJB2022.17505

Kamdem Thiomo Diane, Djuidje Ngounoue Marceline, Tchinda Fossi Cedric, Kenfack Momo Raoul, Martin Ndinakie Yakum, Ambassa Axel Cyriaque, Tsasse Martine Augusta Flore, Assam Assam Jean Paul, Pr Penlap Beng Veronique. Published Online: September 2022  DOI:10.5897/AJB2022.17505

Nana Djeunga HC, Wafeu Sadeu G, Sumo L, Ngo Teke G, Akono Nantia E, Chesnais CB. Managing tropical diseases in Cameroon in the context of COVID‐19: preparedness and dilemma. In Akumbu PW, Nzweundji JG, Eds. Responding to Disease Outbreak in Cameroon: lessons from COVID-19. Rüdiger Köppe Verlag Köln. In press.


Sumo L, Ngum H. Ntonifor, Afor-Aza’ah R, Bopda J, Bamou Heumou R, Ondoua Nganjou GS, Nana‑Djeunga HC (2021). Loiasis is endemic in the Ndikinimeki Health District (Centre Region, Cameroon) but does not represent a hindrance to onchocerciasis elimination. Acta Tropica 225 (2022): 106218


To view more articles, click here

Hugues.C Nana Djeunga one of the judges American Society of Tropical Medicine and Hygiene (ASTMH) Young Investigator Awards Committee.

Remise de la médaille de Chevalier de l'Ordre de la Valeur à titre exceptionnel décernée par le Chef de l'Etat du Cameroun au Prof. Joseph KAMGNO.
Introduction to empirical population genetics to support elimination of tropical disesases
13 - 21 September 2022, CRFilMT Amphiteatre
Visit of the KfW MTN Programme team (German bank that finances projects to fight Neglected Tropical Diseases). KfW's MTN projects are housed at OCEAC in Cameroon, and led by Drs Savadogo and Ngassa.
Visit Regional Health Advisor SCAC
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Our Team


Pr. Joseph Kamgno

CEO of the Higher Institute for Scientific and Medical Research (ISM)

Dr. Hugues Nana

Dr. Hugues Nana Djeunga

Lab Coordinator of the Higher Institute for Scientific and Medical Research (ISM)

photo Guy Wafeu

Dr. Guy Wafeu

Head of clinical unit, Higher Institute for Scientific and Medical Research (ISM)

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